Pemanfaatan Penawar Sampai (Tinospora crispa L.) sebagai Tanaman Obat Tradisional oleh Suku Dayak Ngaju

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Antioxidant properties of flavonoids

Flavonoids, metabolit sekunder terbanyak yang bersumber dari tanaman, telah lama dimanfaatkan sebagai obat tradisional dan secara ilmiah juga telah terbukti memiliki efek farmakologi. Senyawa ini juga memiliki beragam manfaat terhadap kesehatan sehingga sangat berpotensi sebagai bahan baku untuk pengembangan obat baru. Penelitian terbaru memaparkan pemanfaatan flavonoids sebagai antioksidan unt...

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Tinospora crispa (L.) Hook. f. & Thomson: A Review of Its Ethnobotanical, Phytochemical, and Pharmacological Aspects

Tinospora crispa (L.) Hook. f. & Thomson (Menispermaceae), found in the rainforests or mixed deciduous forests in Asia and Africa, is used in traditional medicines to treat numerous health conditions. This review summarizes the up-to-date reports about the ethnobotany, phytochemistry, pharmacological activities, toxicology, and clinical trials of the plant. It also provides critical assessment ...

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Anticholinesterase inhibitory activity of quaternary alkaloids from Tinospora crispa.

Quaternary alkaloids are the major alkaloids isolated from Tinospora species. A previous study pointed to the necessary presence of quaternary nitrogens for strong acetylcholinesterase (AChE) inhibitory activity in such alkaloids. Repeated column chromatography of the vine of Tinospora crispa extract led to the isolation of one new protoberberine alkaloid, 4,13-dihydroxy-2,8,9-trimethoxydibenzo...

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Randomized controlled trial of Tinospora crispa for additional therapy in patients with type 2 diabetes mellitus.

A randomized double blind placebo controlled trial was conducted to determine the efficacy of Tinospora crispa as additional treatment in patients with type 2 diabetes mellitus who did not respond to oral hypoglycemic drugs and refused insulin injection. Twenty patients were allocated to receive Tinospora crispa powder in capsule form at a dosage of 1 gram thrice daily for 6 months. Twenty pati...

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Effect of Tinospora crispa on thioacetamide-induced liver cirrhosis in rats

OBJECTIVES This study was conducted to determine the effect of ethanolic extract of the dried stems of Tinospora crispa in a male rat model of hepatic fibrosis caused by the hepatotoxin, thioacetamide. MATERIALS AND METHODS The extract was gavaged daily to the rats, at doses of 100 and 200 mg/kg along with thioacetamide at a dose of 200 mg/kg twice weekly. To assess the effectivity of extract...

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ژورنال

عنوان ژورنال: Jurnal Pharmascience

سال: 2020

ISSN: 2460-9560,2355-5386

DOI: 10.20527/jps.v7i2.8799